Searchable abstracts of presentations at key conferences in endocrinology

ea0084ps2-09-83 | Thyroid Hormone ACTION | ETA2022

FAM83B is involved in thyroid cancer cell differentiation and migration

Cirello Valentina , Stellaria Grassi Elisa , Pogliaghi Gabriele , Ghiandai Viola , Ermellino Laura , Muzza Marina , Gazzano Giacomo , Persani Luca , Colombo Carla , Fugazzola Laura

FAM83B has been recently identified as an oncogene involved in the development and progression of several malignancies, but its role in thyroid cancers (TC) is still unclear. In the present study, we examined the expression of FAM83B and its possible involvement in cell migration and differentiation, in neoplastic and normal thyroid tissues and in TC human cell lines. We found that FAM83B expression in TC varies according to tumor histotype, being si...